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Find out more about Aktivate Scheduling Contact us at: support aktivate com [8] An example in humans of a dominant lethal allele is Huntington's disease, a rare neurodegenerative disorder that ultimately results in premature death However, because of its late-onset (i e , often after the affected individual reaches reproductive ability), it is able to be maintained in populations Find out more about Aktivate Scheduling Contact us at: support aktivate com en wikipedia org wiki Trinucleotide_repeat_expansionSeveral inheritable neurodegenerative disorders, the polyglutamine diseases, occur if a mutation causes a polyglutamine tract in a specific gene to become too long Important examples of polyglutamine diseases are spinocerebellar ataxia and Huntington's disease See the Motor Neuron Fact Sheet [1] for details regarding other motor neuron diseases Neurodegenerative diseases of the central nervous system can affect the brain and spinal cord This article will cover the epigenetics and treatment of Alzheimer's disease (AD), Huntington's disease (HD), and Parkinson's disease (PD) en wikipedia org wiki Slipped_strand_mispairingTrinucleotide repeat expansion is a cause of a number of human diseases including fragile X syndrome, Huntington's disease, several spinocerebellar ataxias, myotonic dystrophy and Friedrich ataxia en wikipedia org wiki Lethal_allele School Page Tournaments Leagues Divisions Teams School District Standings ScheduleGalaxy › Johnson City › (B) V Basketball › Game Boys Varsity Basketball Maine-Endwell Huntington's disease (HD), also known as Huntington's chorea, is a fatal neurodegenerative disease [7] that is mostly inherited [8] It typically presents as a triad of progressive psychiatric, cognitive, and motor symptoms [9]Trinucleotide repeat disorders generally show genetic anticipation: their severity increases with each successive generation that inherits them This is likely explained by the addition of CAG repeats in the affected gene as the gene is transmitted from parent to child For example, Huntington's disease occurs when there are more than 35 CAG repeats on the gene coding for the protein HTT A Feb 13, 2025 · Maine-Endwell HS Gym directions Get Directions SHOW LOCATION Back to the team page General information Maine-Endwell HS Turf directions Get Directions SHOW LOCATION en wikipedia org wiki Huntington%27s_disease Maine-Endwell 750 Farm To Market Rd Endwell, NY, 13760 (607) 786-8207 me stier org Athletics Director: KEVIN HORES khores me stier org Assistant: SHELLY GOLDSTONE SGoldstone me stier org Export RSS Export Calendar en wikipedia org wiki Polyglutamine_tracten wikipedia org wiki Epigenetics_of_neurodegenerative_diseases (B) JV Basketball Susquehanna Valley (B) JV Basketball Maine Endwell General information Maine-Endwell HS Gym directions Get Directions SHOW LOCATION Paternal transmission is almost always responsible for large repeat transmission resulting in the early onset of Huntington's Disease while maternal transmission results in affected individuals experiencing symptom onset mirroring that of their mother , [32][34] While this transmission of a trinucleotide repeat expansion is regarded to be a In genetics, anticipation is a phenomenon whereby as a genetic disorder is passed on to the next generation, the symptoms of the genetic disorder become apparent at an earlier age with each generation In most cases, an increase in the severity of symptoms is also noted Anticipation is common in trinucleotide repeat disorders, such as Huntington's disease and myotonic dystrophy, where a en wikipedia org wiki Trinucleotide_repeat_disorder Leagues Divisions of Maine-Endwell2025 - 2026 Find out more about Aktivate Scheduling Contact us at: support aktivate com en wikipedia org wiki Anticipation_(genetics) ScheduleGalaxy › Maine-Endwell › School teamsTeams
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